UBR5 anticorps (Ubiquitin Protein Ligase E3 Component N-Recognin 5) (AA 600-650)

Details for Product anti-UBR5 Antibody No. ABIN151138
Antigène
  • DD5
  • EDD
  • EDD1
  • HYD
  • 4432411E13Rik
  • AW549941
  • C77315
  • D030042K14
  • Edd
  • Edd1
  • mKIAA0896
  • Dd5
  • Rat100
  • ubiquitin protein ligase E3 component n-recognin 5
  • UBR5
  • Ubr5
Épitope
AA 600-650
30
8
4
3
3
2
1
1
1
1
Reactivité
Humain, Souris
93
54
26
11
9
6
5
4
4
4
2
1
1
1
1
Hôte
Lapin
70
21
3
1
Clonalité
Polyclonal
Conjugué
Cet anticorp UBR5 est non-conjugé
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
52
47
47
21
13
6
3
3
1
Options
Immunogène The immunogen recognized by this antibody maps to a region between residues 600 and 650 of human E3 Ubiquitin Protein Ligase, HECTdomain containing, 1 using the numbering given in entry NP_056986.2 (GeneID 51366)
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others UBR5 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation UBR5/EDD (UBR5 Antibody Extrait)
Sujet Gene Symbol: UBR5
Poids moléculaire Theoretical MW: 309 kDa
ID gène 51366
NCBI Accession NP_056986
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway
Indications d'application Western Blot 1:2000-1:10000, Immunohistochemistry 1:500 - 1:2000, Immunocytochemistry/Immunofluorescence 1:250 - 1:1000, Immunoprecipitation 2 - 10 μg/mg of lysate, Immunohistochemistry-Paraffin 1:500 - 1:2000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do not freeze.
Stock 4 °C
Stockage commentaire Store at 4°C. Do not freeze.
Images (Fournisseur)
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Detection of EDD1 by Western Blot and Immunoprecipitation. Samples: A. Whole lysate f...
Immunoprecipitation (IP) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Immunoprecipitation: UBR5/EDD Antibody [ABIN151138] - Samples: Whole cell lysate from...
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Western Blot: UBR5/EDD Antibody [ABIN151138] - Whole cell lysate (50 ug) from HeLa an...
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Western Blot: UBR5/EDD Antibody [ABIN151138] - Whole cell lysate (50 ug) from mouse N...
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Western Blot: UBR5/EDD Antibody - Detection of Human EDD1 by Western Blot. Samples: ...
Immunocytochemistry (ICC) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Immunohistochemistry: UBR5/EDD Antibody - Sample: FFPE section of mouse renal cell c...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Immunohistochemistry-Paraffin: UBR5/EDD Antibody - FFPE section of human lung carcin...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Immunohistochemistry-Paraffin: UBR5/EDD Antibody - FFPE section of human prostate ca...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Immunohistochemistry-Paraffin: UBR5/EDD Antibody - FFPE section of mouse teratoma. A...
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody (ABIN151138) Western Blot: UBR5/EDD Antibody - Whole cell lysate (50 ug) from HeLa, 293T, and mou...
Produit citée dans: Oliver Metzig, Fuchs, Tagscherer, Gröne, Schirmacher, Roth: "Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB." dans: Oncogene, Vol. 35, Issue 26, pp. 3399-409, 2016 (PubMed). (Échantillon (espèces): Human). Détails: Western Blotting

Odagiri, Tanji, Mori, Kakita, Takahashi, Kamitani, Wakabayashi: "Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin-proteasome system, autophagy and aggresome formation." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 3, pp. 261-6, 2012 (PubMed).

Christofferson, Li, Hitomi, Zhou, Upperman, Zhu, Gerber, Gygi, Yuan: "A novel role for RIP1 kinase in mediating TNFα production." dans: Cell death & disease, Vol. 3, pp. e320, 2012 (PubMed). (Échantillon (espèces): Human). Détails: Western Blotting

Ling, Lin: "EDD inhibits ATM-mediated phosphorylation of p53." dans: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 14972-82, 2011 (PubMed).

Dompe, Rivers, Li, Cordes, Schwickart, Punnoose, Amler, Seshagiri, Tang, Modrusan, Davis: "A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 43, pp. E943-51, 2011 (PubMed).

Nash, Chen, Salganik, Muzyczka: "Identification of cellular proteins that interact with the adeno-associated virus rep protein." dans: Journal of virology, Vol. 83, Issue 1, pp. 454-69, 2008 (PubMed).

OBrien, Davies, Scurry, Smith, Barton, Henderson, Saunders, Gloss, Patterson, Clancy, Heinzelmann-Schwarz, Murali, Scolyer, Zeng, Williams, Scurr, Defazio, Quinn, Watts, Hacker, Henshall, Sutherland: "The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro." dans: British journal of cancer, Vol. 98, Issue 6, pp. 1085-93, 2008 (PubMed).

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