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DKC1 anticorps (AA 245-514)

DKC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1512829
  • Antigène Voir toutes DKC1 Anticorps
    DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
    Épitope
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-514
    Reactivité
    • 73
    • 34
    • 26
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 71
    • 3
    • 1
    Lapin
    Clonalité
    • 64
    • 11
    Polyclonal
    Conjugué
    • 33
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DKC1 est non-conjugé
    Application
    • 55
    • 26
    • 26
    • 24
    • 14
    • 14
    • 12
    • 10
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    ELRRVRSGVM SEKDHMVTMH DVLDAQWLYD NHKDESYLRR VVYPLEKLLT SHKRLVMKDS AVNAICYGAK IMLPGVLRYE DGIEVNQEIV VITTKGEAIC MAIALMTTAV ISTCDHGIVA KIKRVIMERD TYPRKWGLGP KASQKKLMIK QGLLDKHGKP TDSTPATWKQ EYVDYSESAK KEVVAEVVKA PQVVAEAAKT AKRKRESESE SDETPPAAPQ LIKKEKKKSK KDKKAKAGLE SGAEPGDGDS DTTKKKKKKK KAKEVELVSE
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
    Autre désignation
    DKC1 (DKC1 Produits)
    Synonymes
    anticorps CBF5, anticorps DKC, anticorps DKCX, anticorps NAP57, anticorps NOLA4, anticorps XAP101, anticorps dyskerin, anticorps fv62a07, anticorps wu:fa28f10, anticorps wu:fc87a02, anticorps wu:fi24a05, anticorps wu:fv62a07, anticorps zgc:110395, anticorps DKC1, anticorps cbf5, anticorps dkc, anticorps nap57, anticorps nola4, anticorps xap101, anticorps BC068171, anticorps Nap57, anticorps AtCBF5, anticorps AtNAP57, anticorps homologue of NAP57, anticorps dyskerin pseudouridine synthase 1, anticorps microRNA 664b, anticorps dyskeratosis congenita 1, dyskerin, anticorps dyskeratosis congenita 1, dyskerin L homeolog, anticorps homologue of NAP57, anticorps DKC1, anticorps MIR664B, anticorps dkc1, anticorps dkc1.L, anticorps Dkc1, anticorps NAP57
    Sujet
    This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.,DKC1,CBF5,DKC,DKCX,NAP57,NOLA4,XAP101,Epigenetics & Nuclear Signaling,RNA Binding,DKC1
    Poids moléculaire
    47 kDa/57 kDa
    ID gène
    1736
    UniProt
    O60832
    Pathways
    Telomere Maintenance
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