PTPN22 anticorps (AA 1-90)

N° du produit ABIN1513449

Détail du produit anti-PTPN22 anticorps

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Épitope: AA 1-90

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN22 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MDQREILQKF LDEAQSKKIT KEEFANEFLK LKRQSTKYKA DKTYPTTVAE KPKNIKKNRY KDILPYDYSR VELSLITSDE DSSYINANFI

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_036543.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPN22

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Autre désignation: PTPN22 (PTPN22 Produits)

Synonymes: anticorps 70zpep, anticorps PEP, anticorps Ptpn8, anticorps LYP, anticorps LYP1, anticorps LYP2, anticorps PTPN8, anticorps protein tyrosine phosphatase, non-receptor type 22 (lymphoid), anticorps protein tyrosine phosphatase, non-receptor type 22, anticorps Ptpn22, anticorps PTPN22

Sujet: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.,PTPN22,LYP,LYP1,LYP2,PEP,PTPN22.5,PTPN22.6,PTPN8,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PTPN22

Poids moléculaire: 20 kDa/75 kDa/78 kDa/85 kDa/88 kDa/91 kDa

ID gène: 26191

UniProt: Q9Y2R2