FOXO3 anticorps (Forkhead Box O3) (C-Term)

Details for Product anti-FOXO3 Antibody No. ABIN152045
Antigène
Épitope
C-Term
59
45
25
19
17
10
10
10
10
9
9
9
8
8
8
7
7
7
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
363
219
189
13
11
8
7
7
6
6
6
4
3
3
3
1
1
Hôte
Lapin
306
53
7
1
Clonalité
Polyclonal
Conjugué
Cet anticorp FOXO3 est non-conjugé
21
15
15
15
15
15
15
8
7
5
5
5
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
259
168
139
80
72
27
17
15
13
8
5
4
4
2
1
1
Options
Immunogène The immunogen recognized by this antibody maps to a region between residue 625 and the C-terminus (residue 673) of human Forkhead Box O3a using the numbering given in Swiss-Prot entry O43524 (GeneID 2309).
Specificité This antibody is specific for human FOXO3a protein.
Purification Immunogen affinity purified
Antigène
Autre désignation FOXO3 (FOXO3 Antibody Extrait)
Sujet Gene Symbol: FOXO3
Poids moléculaire Theoretical MW: 71.3 kDa
ID gène 2309
UniProt O43524
Pathways Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Indications d'application Western Blot 1:5000-1:15000, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:250 - 1:1000, Immunoprecipitation 2-5 μg/mg lysate, Immunohistochemistry-Paraffin 1:500 - 1:2000Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: 2 to 5 μg/mg lysate Histo/Cytochemistry: not tested *In some cases, the antibody may be diluted further than indicated. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do not freeze.
Stock 4 °C
Stockage commentaire Store at 4°C. Do not freeze.
Images (Fournisseur)
Image no. 1 for anti-Forkhead Box O3 (FOXO3) (C-Term) antibody (ABIN152045) Detection of Human FOXO3a by Western Blot and Immunoprecipitation. Samples: Whole cel...
Image no. 2 for anti-Forkhead Box O3 (FOXO3) (C-Term) antibody (ABIN152045) Immunohistochemistry-Paraffin: FOXO3 Antibody [ABIN152045] - FFPE section of human br...
Image no. 3 for anti-Forkhead Box O3 (FOXO3) (C-Term) antibody (ABIN152045) Immunohistochemistry-Paraffin: FOXO3 Antibody [ABIN152045] - FFPE section of mouse re...
Image no. 4 for anti-Forkhead Box O3 (FOXO3) (C-Term) antibody (ABIN152045) Immunohistochemistry-Paraffin: FOXO3 Antibody [ABIN152045] - Section of human ovarian...
Image no. 5 for anti-Forkhead Box O3 (FOXO3) (C-Term) antibody (ABIN152045) Immunocytochemistry/Immunofluorescence: FOXO3 Antibody [ABIN152045] - Analysis of FOX...
Produit citée dans: Oh, Paik: "Genetic Ablation of FOXO in Mice to Investigate Its Physiological Role." dans: Methods in molecular biology (Clifton, N.J.), Vol. 1890, pp. 239-248, 2019 (PubMed). (Échantillon (espèces): Mouse (Murine)).

Srivastava, Diba, Dean, Banine, Shaver, Hagen, Gong, Su, Emery, Marks, Harris, Baggenstoss, Weigel, Sherman, Back: "A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors." dans: The Journal of clinical investigation, Vol. 128, Issue 5, pp. 2025-2041, 2018 (PubMed).

Hwang, Oh, Santo, Kim, Chen, Bronson, Locasale, Na, Lee, Reed, Toth, Yu, Muller, Paik: "FOXO protects against age-progressive axonal degeneration." dans: Aging cell, Vol. 17, Issue 1, 2017 (PubMed). Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)).

Lin, Jan, Kuo: "Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine." dans: Molecular pharmaceutics, Vol. 12, Issue 8, pp. 2858-68, 2015 (PubMed).