Tyrosine Hydroxylase (TH) anticorps

Détails pour le produit réf. ABIN152459
Antigène
  • DYT14
  • DYT5b
  • TYH
  • The
  • CG10118
  • DH65B
  • DTH
  • Dmel\\CG10118
  • Pale
  • Ple
  • TH
  • Th
  • VII
  • dTH1
  • dTH65B
  • pale/ple
  • th
  • dyt14
  • dyt5b
  • tyh
  • tyrosine hydroxylase
  • pale
  • tyrosine 3-monooxygenase
  • tyrosine hydroxylase S homeolog
  • TH
  • Th
  • ple
  • th
  • th.S
Reactivité
Oiseau, Humain, Mammifères, Souris, Lapin, Rat (Rattus), Reptile
260
241
174
19
18
16
11
10
5
3
3
3
3
3
2
1
1
1
1
1
Hôte
Mouton
259
49
16
14
10
Clonalité
Polyclonal
Conjugué
Inconjugué
10
6
6
6
6
6
6
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Free Floating) (IHC (ff)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
266
184
141
67
53
38
37
27
17
14
13
7
3
2
2
Options
Immunogène Native rat tyrosine hydroxylase, purified from pheochromocytoma.
Specificité Specific for the ~60k tyrosine hydroxylase protein.
Purification Immunogen affinity purified
Antigène
Autre désignation Tyrosine Hydroxylase (TH Antibody Extrait)
Sujet Gene Symbol: TH
Poids moléculaire Theoretical MW: 60 kDa
ID gène 7054
UniProt P04177
Pathways Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Indications d'application Western Blot 1:1000, Immunohistochemistry 1:1000, Immunocytochemistry/Immunofluorescence 1:1000, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1:1000, Immunohistochemistry Free-Floating, Immunofluorescence 1:10 - 1:500Immunocytochemistry use reported in literature (PMID: 21694758). Immunohistochemistry-Paraffin use reported in literature (PMID: 23690557). Use in Immunohistochemistry free-floating reported in scientific literature (PMID 26553597). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.15 mg/mL
Buffer 10 mM HEPES ( pH 7.5), 0.15M NaCl, 0.1 mg/mL BSA and 50 % Glycerol
Buffer contains: No Preservative
Agent conservateur Without preservative
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock -20 °C
Stockage commentaire Store at -20°C. Avoid freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Detection of tyrosine hydroxylase in PC12 cell lysate using ABIN152459.
Western Blotting (WB) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Western Blot: Tyrosine Hydroxylase Antibody [ABIN152459] - Analysis of rat caudate ly...
Immunofluorescence (IF) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152459] - ...
Immunofluorescence (IF) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152459] - ...
Immunocytochemistry (ICC) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Immunocytochemistry: Tyrosine Hydroxylase Antibody - 10x Magnificatio Mouse cryo-sec...
Western Blotting (WB) image for anti-Tyrosine Hydroxylase (TH) antibody (ABIN152459) Western Blot: Tyrosine Hydroxylase Antibody - Mice were injected with PBS (control g...
Produit citée dans: Theofilopoulos, Abreu de Oliveira, Yang, Yutuc, Saeed, Abdel-Khalik, Ullgren, Cedazo-Minguez, Björkhem, Wang, Griffiths, Arenas: "24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo." dans: The Journal of biological chemistry, Vol. 294, Issue 11, pp. 4169-4176, 2019 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Kastriti, Kameneva, Kamenev, Dyachuk, Furlan, Hampl, Memic, Marklund, Lallemend, Hadjab, Calvo-Enrique, Ernfors, Fried, Adameyko: "Schwann Cell Precursors Generate the Majority of Chromaffin Cells in Zuckerkandl Organ and Some Sympathetic Neurons in Paraganglia." dans: Frontiers in molecular neuroscience, Vol. 12, pp. 6, 2019 (PubMed). Méthode utilisée: Immunofluorescence (fixed cells) (IF/ICC) (Échantillon (espèces): Mouse (Murine)).

Shah, Maric, Denaro, Ibrahim, Mason, Kumar, Hammoud, Reid: "Nitrosative Stress Is Associated with Dopaminergic Dysfunction in the HIV-1 Transgenic Rat." dans: The American journal of pathology, Vol. 189, Issue 7, pp. 1375-1385, 2019 (PubMed).

Abdellah, van Remoortel, Mohey-Elsaeed, Mustafa, Ahmed, Timmermans, Buckinx: "Neuropeptide AF Induces Piecemeal Degranulation in Murine Mucosal Mast Cells: A New Mediator in Neuro-Immune Communication in the Intestinal Lamina Propria?" dans: Anatomical record (Hoboken, N.J. : 2007), Vol. 301, Issue 6, pp. 1103-1114, 2018 (PubMed).

Dai, Chen, Sakata: "EGR-1 Expression in Catecholamine-synthesizing Neurons Reflects Auditory Learning and Correlates with Responses in Auditory Processing Areas." dans: Neuroscience, Vol. 379, pp. 415-427, 2018 (PubMed).

Shaltouki, Hsieh, Kim, Wang: "Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models." dans: Acta neuropathologica, Vol. 136, Issue 4, pp. 607-620, 2018 (PubMed).

Okawa, Saltó, Ravichandran, Yang, Toledo, Arenas, Del Sol: "Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift." dans: Nature communications, Vol. 9, Issue 1, pp. 2595, 2018 (PubMed).

Milanese, Cerri, Ulusoy, Gornati, Plat, Gabriels, Blandini, Di Monte, Hoeijmakers, Mastroberardino: "Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease." dans: Cell death & disease, Vol. 9, Issue 8, pp. 818, 2018 (PubMed).

Barr, Woolley: "Developmental auditory exposure shapes responses of catecholaminergic neurons to socially-modulated song." dans: Scientific reports, Vol. 8, Issue 1, pp. 11717, 2018 (PubMed).

García-Domínguez, Veselá, García-Revilla, Carrillo-Jiménez, Roca-Ceballos, Santiago, de Pablos, Venero: "Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease." dans: Frontiers in cellular neuroscience, Vol. 12, pp. 398, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Kabelik, Weitekamp, Choudhury, Hartline, Smith, Hofmann: "Neural activity in the social decision-making network of the brown anole during reproductive and agonistic encounters." dans: Hormones and behavior, Vol. 106, pp. 178-188, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Reptile).

Luan, Hammond, Vuillermot, Meyer, Eyles: "Maternal Vitamin D Prevents Abnormal Dopaminergic Development and Function in a Mouse Model of Prenatal Immune Activation." dans: Scientific reports, Vol. 8, Issue 1, pp. 9741, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Jalewa, Sharma, Gengler, Hölscher: "A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease." dans: Neuropharmacology, Vol. 117, pp. 238-248, 2017 (PubMed).

Skrzypecki, Gawlak, Huc, Szulczyk, Ufnal: "Renal denervation decreases blood pressure and renal tyrosine hydroxylase but does not augment the effect of hypotensive drugs." dans: Clinical and experimental hypertension (New York, N.Y. : 1993), Vol. 39, Issue 3, pp. 290-294, 2017 (PubMed). (Échantillon (espèces): Rat (Rattus)).

Chen, Clark, Woolley: "Courtship song preferences in female zebra finches are shaped by developmental auditory experience." dans: Proceedings. Biological sciences, Vol. 284, Issue 1855, 2017 (PubMed).

Dulcis, Lippi, Stark, Do, Berg, Spitzer: "Neurotransmitter Switching Regulated by miRNAs Controls Changes in Social Preference." dans: Neuron, Vol. 95, Issue 6, pp. 1319-1333.e5, 2017 (PubMed). (Échantillon (espèces): Amphibian).

Kim, Kang, Lee, Park, Jo, Khang, Shin: "Identification of transketolase as a target of PARIS in substantia nigra." dans: Biochemical and biophysical research communications, Vol. 493, Issue 2, pp. 1050-1056, 2017 (PubMed). (Échantillon (espèces): Human).

Rivetti di Val Cervo, Romanov, Spigolon, Masini, Martín-Montañez, Toledo, La Manno, Feyder, Pifl, Ng, Sánchez, Linnarsson, Wernig, Harkany, Fisone, Arenas: "Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model." dans: Nature biotechnology, Vol. 35, Issue 5, pp. 444-452, 2017 (PubMed). Méthode utilisée: Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (IHC) (Échantillon (espèces): Human).

Friend, Weed, Sandoval, Nufer, Ostlund, Edwards: "CB1-Dependent Long-Term Depression in Ventral Tegmental Area GABA Neurons: A Novel Target for Marijuana." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 45, pp. 10943-10954, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Hodson, Nicholls, Turner, Llyr, Fielding, Douglas, Ratnayaka, Robbins, Pugh, Buckler, Ratcliffe, Bishop: "Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway." dans: The Journal of physiology, Vol. 594, Issue 5, pp. 1179-95, 2016 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Immunohistochemistry (Paraffin-embedded Sections)

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