tyrosine Hydroxylase (TH) (pSer40) anticorps

Détails pour le produit réf. ABIN152518, Fournisseur: Connectez-vous pour afficher
Antigène
  • DYT14
  • DYT5b
  • TYH
  • The
  • CG10118
  • DH65B
  • DTH
  • Dmel\\CG10118
  • Pale
  • Ple
  • TH
  • Th
  • VII
  • dTH1
  • dTH65B
  • pale/ple
  • th
  • dyt14
  • dyt5b
  • tyh
  • tyrosine hydroxylase
  • pale
  • tyrosine 3-monooxygenase
  • tyrosine hydroxylase S homeolog
  • TH
  • Th
  • ple
  • th
  • th.S
Épitope
pSer40
42
28
25
24
17
16
6
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Souris, Rat (Rattus)
235
211
152
20
19
18
11
11
5
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Hôte
Lapin
234
51
16
15
10
Clonalité
Polyclonal
Conjugué
Inconjugué
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
279
190
147
67
54
40
40
28
18
15
13
7
4
3
2
1
Options
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N° du produit (Fournisseur)
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Immunogène Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser40 of rat tyrosine hydroxylase.
Specificité Specific for the ~60k tyrosine hydroxylase protein phosphorylated at Ser40. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.
Purification Immunogen affinity purified
Antigène
Autre désignation Tyrosine Hydroxylase (TH Antibody Extrait)
Sujet Gene Symbol: TH
Poids moléculaire Theoretical MW: 60 kDa
ID gène 7054
UniProt P04177
Pathways Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Indications d'application Western Blot 1:1000, Immunohistochemistry 1:1000, Immunocytochemistry/Immunofluorescence 1:1000, Immunohistochemistry-Frozen 1:1000, Immunofluorescence 1:10-1:500It has specifically been tested in PC12 lysates stimulated by okadaic acid. Depending upon brain region being studied, protein loads, and detection methods used, some higher bands may be detected.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer 10 mM HEPES ( pH 7.5), 0.15M NaCl, 0.1 mg/mL BSA and 50 % Glycerol
Buffer contains: No Preservative
Agent conservateur Without preservative
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock -20 °C
Stockage commentaire Store at -20°C. Avoid freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-tyrosine Hydroxylase (TH) (pSer40) antibody (ABIN152518) anti-tyrosine Hydroxylase (TH) (pSer40) antibody
Immunohistochemistry (IHC) image for anti-tyrosine Hydroxylase (TH) (pSer40) antibody (ABIN152518) Immunohistochemistry: Tyrosine Hydroxylase [p Ser40] Antibody [ABIN152518] - Immunohi...
Western Blotting (WB) image for anti-tyrosine Hydroxylase (TH) (pSer40) antibody (ABIN152518) Western Blot: Tyrosine Hydroxylase [p Ser40] Antibody [ABIN152518] - Western blot ana...
 image for anti-tyrosine Hydroxylase (TH) (pSer40) antibody (ABIN152518) Tyrosine Hydroxylase Antibody - Western blot of recombinant phospho-TH and non-phos...
Produit citée dans: Gassmann, Pfistner, Doan, Vogel, Soliz: "Impaired ventilatory acclimatization to hypoxia in female mice overexpressing erythropoietin: unexpected deleterious effect of estradiol in carotid bodies." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 299, Issue 6, pp. R1511-20, 2010 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen Sections)

Soliz, Joseph, Soulage, Becskei, Vogel, Pequignot, Ogunshola, Gassmann: "Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies." dans: The Journal of physiology, Vol. 568, Issue Pt 2, pp. 559-71, 2005 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Immunohistochemistry

Salvatore, Garcia-Espana, Goldstein, Deutch, Haycock: "Stoichiometry of tyrosine hydroxylase phosphorylation in the nigrostriatal and mesolimbic systems in vivo: effects of acute haloperidol and related compounds." dans: Journal of neurochemistry, Vol. 75, Issue 1, pp. 225-32, 2000 (PubMed).

Witkovsky, Gabriel, Haycock, Meller: "Influence of light and neural circuitry on tyrosine hydroxylase phosphorylation in the rat retina." dans: Journal of chemical neuroanatomy, Vol. 19, Issue 2, pp. 105-16, 2000 (PubMed). Détails: Immunohistochemistry (Frozen Sections)

Lew, Garcia-Espana, Lee, Carr, Goldstein, Haycock, Meller: "Increased site-specific phosphorylation of tyrosine hydroxylase accompanies stimulation of enzymatic activity induced by cessation of dopamine neuronal activity." dans: Molecular pharmacology, Vol. 55, Issue 2, pp. 202-9, 1999 (PubMed).

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