PCLO anticorps

N° du produit ABIN1526066

Détail du produit anti-PCLO anticorps

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCLO est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein-A affinity chromatography

Clone: PCLO-01

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), approx. pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PCLO

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Autre désignation: PCLO (PCLO Produits)

Synonymes: anticorps pclo, anticorps wu:fj53e09, anticorps Acz, anticorps Pico, anticorps mKIAA0559, anticorps aczonin, anticorps PCLO, anticorps ACZ, anticorps piccolo presynaptic cytomatrix protein, anticorps piccolo presynaptic cytomatrix protein a, anticorps piccolo (presynaptic cytomatrix protein), anticorps PCLO, anticorps pcloa, anticorps Pclo, anticorps LOC768552

Sujet: PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion. Synonyms: ACZ, Aczonin, KIAA0559, Protein piccolo

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis