SCARB1 anticorps (Scavenger Receptor Class B, Member 1) (C-Term)

Details for Product anti-SCARB1 Antibody No. ABIN152899, Fournisseur: Connectez-vous pour afficher
Antigène
  • cb1015
  • SCARB1
  • Scarb1
  • CD36L1
  • CLA-1
  • CLA1
  • HDLQTL6
  • SR-BI
  • SRB1
  • AI120173
  • CD36
  • Cd36l1
  • Cla-1
  • Cla1
  • D5Ertd460e
  • Hdlq1
  • Hlb398
  • SR-B1
  • SRBI
  • Srb1
  • mSR-BI
  • scavenger receptor class B, member 1
  • scavenger receptor class B member 1
  • scarb1
  • SCARB1
  • Scarb1
  • CpipJ_CPIJ014332
  • CpipJ_CPIJ019101
Épitope
C-Term, AA 400-509
16
15
12
5
5
2
2
2
1
1
1
1
Reactivité
Hamster, Humain, Souris, Rat (Rattus), Écureuil, Mustélidé
84
43
40
2
2
2
2
1
Hôte
Chèvre
76
17
14
Clonalité
Polyclonal
Conjugué
Cet anticorp SCARB1 est non-conjugé
4
4
3
3
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
90
45
41
22
13
12
10
7
6
5
3
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène A synthetic peptide made to the C-terminal region of mouse SR-BI (between residues 400-509). [UniProt# Q61009]
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others SCARB1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SR-BI (SCARB1 Antibody Extrait)
Sujet Gene Symbol: SCARB1
Poids moléculaire Theoretical MW: 82 kDa
ID gène 949
UniProt Q61009
Pathways Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism
Indications d'application Western Blot 1:500, Flow Cytometry, Immunocytochemistry/Immunofluorescence 1:50, Immunohistochemistry-Paraffin, Immunohistochemistry-FrozenThis SR-BI antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is observed at ~ 82 kDa. Flow Cytometry was reported in scientific literature. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24814604) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 26865459).
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 3 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do not freeze.
Stock 4 °C
Stockage commentaire Store at 4°C. Do not freeze.
Images (Fournisseur)
Western Blotting (WB) image for anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 400-509), (C-Term) antibody (ABIN152899) Detection of SR-BI in mouse liver lysate (20 ug) using ABIN152899 (2 ug/ml). ECL det...
Western Blotting (WB) image for anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 400-509), (C-Term) antibody (ABIN152899) Western Blot: SR-BI Antibody [ABIN268868] - WB analysis of SRBI in 1. human liver lys...
Immunofluorescence (IF) image for anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 400-509), (C-Term) antibody (ABIN152899) Immunocytochemistry/Immunofluorescence: SR-BI Antibody [ABIN268868] - SRB1 antibody w...
Produit citée dans: Oldoni, van Capelleveen, Dalila, Wolters, Heeren, Sinke, Hui, Dallinga-Thie, Frikke-Schmidt, Hovingh, van de Sluis, Tybjærg-Hansen, Kuivenhoven et al.: "Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger ..." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 7, pp. 1440-1453, 2018 (PubMed).

Velagapudi, Yalcinkaya, Piemontese, Meier, Nørrelykke, Perisa, Rzepiela, Stebler, Stoma, Zanoni, Rohrer, von Eckardstein: "VEGF-A Regulates Cellular Localization of SR-BI as Well as Transendothelial Transport of HDL but Not LDL." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 5, pp. 794-803, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Human).

Ganesan, Mates, Cheplowitz, Avila, Zimmerer, Yao, Maiseyeu, Rajaram, Robinson, Anderson: "Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells." dans: Scientific reports, Vol. 6, pp. 20646, 2016 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting,Immunohistochemistry (Frozen Sections)

Widjaja-Adhi, Lobo, Golczak, Von Lintig: "A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption." dans: Human molecular genetics, Vol. 24, Issue 11, pp. 3206-19, 2015 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Varatharajalu, Garige, Leckey, Arellanes-Robledo, Reyes-Gordillo, Shah, Lakshman: "Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat." dans: The American journal of pathology, Vol. 184, Issue 7, pp. 2035-44, 2014 (PubMed). (Échantillon (espèces): Rat (Rattus)). Détails: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Dikkers, Freak de Boer, Annema, Groen, Tietge: "Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice." dans: Hepatology (Baltimore, Md.), Vol. 58, Issue 1, pp. 293-303, 2013 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Huang, Zhang, Wang, Jiang, Bao: "MCP-1 impacts RCT by repressing ABCA1, ABCG1, and SR-BI through PI3K/Akt posttranslational regulation in HepG2 cells." dans: Journal of lipid research, Vol. 54, Issue 5, pp. 1231-40, 2013 (PubMed).

de Boer, Annema, Schreurs, van der Veen, van der Giet, Nijstad, Kuipers, Tietge: "Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice." dans: Journal of lipid research, Vol. 53, Issue 3, pp. 348-57, 2012 (PubMed).

Storey, McIntosh, Huang, Landrock, Martin, Landrock, Payne, Atshaves, Kier, Schroeder: "Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 8, pp. G824-39, 2012 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Immunocytochemistry,Western Blotting,Immunofluorescence

Dong, Xie, Zhou, Hu, Chen, Duan, Li, Han: "Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen." dans: Atherosclerosis, Vol. 218, Issue 2, pp. 435-42, 2011 (PubMed).

Akita, Tsujita, Yokota, Gonzalez, Ohte, Kimura, Yokoyama: "High density lipoprotein turnover is dependent on peroxisome proliferator-activated receptor α in mice." dans: Journal of atherosclerosis and thrombosis, Vol. 17, Issue 11, pp. 1149-59, 2010 (PubMed). (Échantillon (espèces): Mouse (Murine)).

Robichaud, van der Veen, Yao, Trigatti, Vance: "Hepatic uptake and metabolism of phosphatidylcholine associated with high density lipoproteins." dans: Biochimica et biophysica acta, Vol. 1790, Issue 6, pp. 538-51, 2009 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Liang, Russell, Yonkers, McDonald, Rodriguez, Harding, Anthony: "Differential effects of hepatitis C virus JFH1 on human myeloid and plasmacytoid dendritic cells." dans: Journal of virology, Vol. 83, Issue 11, pp. 5693-707, 2009 (PubMed). (Échantillon (espèces): Human). Détails: Flow Cytometry

Robichaud, Francis, Vance: "A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase." dans: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35496-506, 2008 (PubMed).

Hashimoto, Suzuki, Taniguchi, Noguchi, Yohda, Odaka: "Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile." dans: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36617-23, 2008 (PubMed).

Akpovi, Yoon, Vitale, Pelletier: "The predominance of one of the SR-BI isoforms is associated with increased esterified cholesterol levels not apoptosis in mink testis." dans: Journal of lipid research, Vol. 47, Issue 10, pp. 2233-47, 2006 (PubMed). (Échantillon (espèces): Mustelid). Détails: Immunocytochemistry,Western Blotting,Immunofluorescence

Bocharov, Baranova, Vishnyakova, Remaley, Csako, Thomas, Patterson, Eggerman et al.: "Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in ..." dans: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36072-82, 2004 (PubMed). (Échantillon (espèces): Human). Détails: Immunocytochemistry,Immunofluorescence

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