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POLR1A anticorps (C-Term)

POLR1A Reactivité: Humain WB Hôte: Lapin Polyclonal RB39202 unconjugated
N° du produit ABIN1536725
  • Antigène Voir toutes POLR1A Anticorps
    POLR1A (Polymerase (RNA) I Polypeptide A, 194kDa (POLR1A))
    Épitope
    • 13
    • 6
    • 1
    • 1
    • 1
    AA 1437-1465, C-Term
    Reactivité
    • 17
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp POLR1A est non-conjugé
    Application
    • 16
    • 13
    • 2
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This POLR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1437-1465 amino acids from the C-terminal region of human POLR1A.
    Clone
    RB39202
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    POLR1A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Antigène
    POLR1A (Polymerase (RNA) I Polypeptide A, 194kDa (POLR1A))
    Autre désignation
    POLR1A (POLR1A Produits)
    Synonymes
    anticorps 194kDa, anticorps 3010014K16Rik, anticorps RPA194, anticorps Rpo1-4, anticorps mRPA1, anticorps Rpa1, anticorps A190, anticorps RPA1, anticorps RPO1-4, anticorps RPO14, anticorps polymerase (RNA) I polypeptide A, anticorps RNA polymerase I subunit A, anticorps Polr1a, anticorps POLR1A
    Sujet
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
    Poids moléculaire
    194811
    ID gène
    25885
    NCBI Accession
    NP_056240
    UniProt
    O95602
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