This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L.
anticorps Mar6, anticorps Mart6, anticorps dJ1033E15.2, anticorps BC058638, anticorps RGD1306472, anticorps retrotransposon Gag like 6, anticorps leucine zipper, down-regulated in cancer 1-like, anticorps RTL6, anticorps Rtl6, anticorps LOC100337805
Sujet
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.