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PDZD3 anticorps (AA 258-285)

PDZD3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB37960 unconjugated
N° du produit ABIN1538201
  • Antigène Voir toutes PDZD3 Anticorps
    PDZD3 (PDZ Domain Containing 3 (PDZD3))
    Épitope
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 258-285
    Reactivité
    • 31
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 26
    • 5
    Lapin
    Clonalité
    • 28
    • 3
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp PDZD3 est non-conjugé
    Application
    • 26
    • 21
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.
    Clone
    RB37960
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDZD3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    PDZD3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Antigène
    PDZD3 (PDZ Domain Containing 3 (PDZD3))
    Autre désignation
    PDZD3 (PDZD3 Produits)
    Synonymes
    anticorps RGD1559807, anticorps zgc:194812, anticorps IKEPP, anticorps NHERF4, anticorps PDZK2, anticorps NaPi-Cap2, anticorps Pdzk2, anticorps PDZ domain containing 3, anticorps PDZ domain containing 3b, anticorps Pdzd3, anticorps pdzd3b, anticorps PDZD3
    Sujet
    Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).
    ID gène
    79849
    NCBI Accession
    NP_001161940, NP_079067
    UniProt
    Q86UT5
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