NLRP4 anticorps (N-Term)

N° du produit ABIN1538995

Détail du produit anti-NLRP4 anticorps

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Épitope: AA 121-149, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NLRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the N-terminal region of human NLRP4.

Clone: RB37352

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NLRP4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur NLRP4

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Autre désignation: NLRP4 (NLRP4 Produits)

Synonymes: anticorps CLR19.5, anticorps CT58, anticorps NALP4, anticorps PAN2, anticorps PYPAF4, anticorps RNH2, anticorps Nalp4, anticorps Nlrp4e, anticorps RGD1563529, anticorps NLR family pyrin domain containing 4, anticorps NLR family, pyrin domain containing 4, anticorps NLRP4, anticorps Nlrp4

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).

Poids moléculaire: 113415

ID gène: 147945

NCBI Accession: NP_604393

UniProt: Q96MN2

Pathways: Inflammasome