HERPUD1 anticorps (N-Term)

N° du produit ABIN1539462

Détail du produit anti-HERPUD1 anticorps

Antigène: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Épitope: AA 55-83, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HERPUD1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.

Clone: RB36972

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: HERPUD1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur HERPUD1

Antigène: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Autre désignation: HERPUD1 (HERPUD1 Produits)

Synonymes: anticorps herpud1-a, anticorps herp, anticorps herpud1, anticorps mif1, anticorps sup, anticorps HERPUD1, anticorps zgc:114134, anticorps HERP, anticorps Mif1, anticorps SUP, anticorps Herp, anticorps Mifl, anticorps Sup, anticorps homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog, anticorps homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog, anticorps homocysteine inducible ER protein with ubiquitin like domain 1, anticorps homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, anticorps herpud1.S, anticorps herpud1.L, anticorps herpud1, anticorps HERPUD1, anticorps Herpud1

Sujet: The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].

Poids moléculaire: 43720

ID gène: 9709

NCBI Accession: NP_001010989, NP_001259032, NP_055500

UniProt: Q15011

Pathways: ER-Nucleus Signaling