This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This FARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the N-terminal region of human FARP1.
anticorps FARP1, anticorps CDEP, anticorps PLEKHC2, anticorps PPP1R75, anticorps AW228844, anticorps BC030329, anticorps Cdep, anticorps FERM, ARH/RhoGEF and pleckstrin domain protein 1, anticorps FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived), anticorps FARP1, anticorps Farp1
Sujet
This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.