Calnexin anticorps (C-Term)

N° du produit ABIN1574057

Détail du produit anti-Calnexin anticorps

Antigène: Calnexin (CANX)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Orang-Utan

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Specificité: Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.

Réactivité croisée (Details): Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide (KLH-coupled) from carboxyl terminal of human calnexin .

Isotype: IgG1

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther applications: user-optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Références pour anticorps anti-Calnexin (ABIN1574057)

Li, Muma: "Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT?A receptor: characterization and subcellular distribution of sumoylated 5-HT?A receptors." dans: Psychoneuroendocrinology, Vol. 38, Issue 11, pp. 2542-53, (2013) (PubMed).

Weber, Chen, Rowin, Mertens, Galvan, Zhi, Dealing, Roman, Banga, Tan, Luo, Samuel: "Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation." dans: Journal of bacteriology, Vol. 195, Issue 17, pp. 3914-24, (2013) (PubMed).

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: Calnexin (CANX Produits)

Synonymes: anticorps CNX, anticorps IP90, anticorps P90, anticorps 1110069N15Rik, anticorps AI988026, anticorps Cnx, anticorps D11Ertd153e, anticorps canx, anticorps clgn, anticorps clnx, anticorps cnx, anticorps PP90, anticorps zgc:63524, anticorps wu:fe06b12, anticorps CANX, anticorps calnexin, anticorps CalNeXin, anticorps calnexin L homeolog, anticorps CANX, anticorps Canx, anticorps cnx-1, anticorps canx.L, anticorps canx, anticorps LOC100283947

Sujet: Calnexin is calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may be involved in assisting protein assembly or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the ER quality control apparatus via the retention of incorrectly folded proteins.Calnexin Antibody, pAb, Rabbit is developed in rabbit hosts using a KLH-coupled synthetic peptide from carboxyl terminal of human calnexin protein (Swiss Prot: P27824).

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis