NEFM anticorps (AA 320-370)

N° du produit ABIN1574095

Détail du produit anti-NEFM anticorps

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Épitope: AA 320-370

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEFM est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Rabbit Anti-Neurofilament-M Polyclonal Antibody detects endogenous levels of mouse and rat Neurofilament-M protein. It is predicted to react with human neurofilament-M according to sequence homology.

Réactivité croisée (Details): Rabbit Anti-Neurofilament-M Polyclonal Antibody detects endogenous levels of mouse and rat Neurofilament-M protein. It is predicted to react with human neurofilament-M according to sequence homology.

Purification: Immunoaffinity chromatography

Immunogène: KLH-coupled synthetic peptide from within AA 320-370 of human Neurofilament-M .

Isotype: IgG

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mLOther Applications: user-optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Détails sur NEFM

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Autre désignation: Neurofilament-M (NEFM Produits)

Synonymes: anticorps NEF3, anticorps NF-M, anticorps NFM, anticorps Nef3, anticorps Nfm, anticorps NF160, anticorps NF165, anticorps nef-m, anticorps nef3, anticorps nefm, anticorps nf-m, anticorps zgc:112359, anticorps nefm-a, anticorps nefm-b, anticorps neurofilament medium, anticorps neurofilament triplet M protein, anticorps neurofilament, medium polypeptide, anticorps neurofilament medium polypeptide, anticorps neurofilament medium L homeolog, anticorps neurofilament, medium polypeptide a, anticorps neurofilament medium S homeolog, anticorps NEFM, anticorps Nefm, anticorps TVAG_582010, anticorps TVAG_379630, anticorps nefm.L, anticorps nefma, anticorps nefm.S

Sujet: Neurofilament-M (also known as NFM), is one member of Neurofilaments, which are the major intermediate filaments found in neurons and consist of light (NFL), medium (NFM), and heavy (NFH) subunits. Being critical for radial axon growth, neurofilaments determine axon caliber while microtubules are involved in axon elongation. It can also be useful in studies of neurofilament accumulations in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease.Rabbit Anti-Neurofilament-M Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from within residues 320-370 of human Neurofilament-M (Swiss Prot: P07197).

Pathways: Brown Fat Cell Differentiation