CSTB anticorps (AA 1-98)

N° du produit ABIN1679392

Détail du produit anti-CSTB anticorps

Antigène: CSTB (Cystatin B (Stefin B) (CSTB))

Épitope: AA 1-98

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSTB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MMCGAPSATQ PATAETQHIA DQVRSQLEEK ENKKFPVFKA VSFKSQVVAG TNYFIKVHVG DEDFVHLRVF QSLPHENKPL TLSNYQTNKA KHDELTYF

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human CSTB (NP_000091.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CSTB

Antigène: CSTB (Cystatin B (Stefin B) (CSTB))

Autre désignation: CSTB (CSTB Produits)

Synonymes: anticorps CST6, anticorps EPM1, anticorps EPM1A, anticorps PME, anticorps STFB, anticorps ULD, anticorps CSTB, anticorps Cyb, anticorps Epm1, anticorps Stfb, anticorps MGC189005, anticorps pme, anticorps cst6, anticorps epm1, anticorps stfb, anticorps AA960480, anticorps ARABIDOPSIS THALIANA PHYTOCYSTATIN 6, anticorps ATCYS6, anticorps ATCYSB, anticorps cystatin B, anticorps LOC100008600, anticorps LOC100136235, anticorps CPI1, anticorps cystatin B, anticorps cystatin B (stefin B), anticorps cystatin 14a, tandem duplicate 2, anticorps cystatin-B, anticorps CSTB, anticorps Cstb, anticorps cstb, anticorps cst14a.2, anticorps CYSB, anticorps cpi1, anticorps LOC101123265

Sujet: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.,CSTB,CPI-B,CST6,EPM1,EPM1A,PME,STFB,ULD,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,CSTB

Poids moléculaire: 11 kDa

ID gène: 1476

UniProt: P04080

Pathways: Response to Water Deprivation