DNAJC2 anticorps (AA 1-140)

N° du produit ABIN1679553

Détail du produit anti-DNAJC2 anticorps

Antigène: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Épitope: AA 1-140

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MLLLPSAADG RGTAITHALT SASTLCQVEP VGRWFEAFVK RRNRNASASF QELEDKKELS EESEDEELQL EEFPMLKTLD PKDWKNQDHY AVLGLGHVRY KATQRQIKAA HKAMVLKHHP DKRKAAGEPI KEGDNDYFTC

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2 (NP_055192.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DNAJC2

Antigène: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Autre désignation: DNAJC2 (DNAJC2 Produits)

Synonymes: anticorps zrf1, anticorps ZRF1, anticorps MPHOSPH11, anticorps MPP11, anticorps ZUO1, anticorps AU020218, anticorps MIDA1, anticorps Zrf1, anticorps Zrf2, anticorps zgc:85671, anticorps DnaJ heat shock protein family (Hsp40) member C2, anticorps DnaJ (Hsp40) homolog, subfamily C, member 2, anticorps dnajc2, anticorps DNAJC2, anticorps Dnajc2

Sujet: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.,DNAJC2,MPHOSPH11,MPP11,ZRF1,ZUO1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor immunology,Tumor-associated antigens,Signal Transduction,Immunology & Inflammation,DNAJC2

Poids moléculaire: 65 kDa/71 kDa

ID gène: 27000

UniProt: Q99543

Pathways: Chromatin Binding