GNB3 anticorps (AA 1-230)

N° du produit ABIN1680055

Détail du produit anti-GNB3 anticorps

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Épitope: AA 1-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNB3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human GNB3 (NP_002066.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GNB3

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Autre désignation: GNB3 (GNB3 Produits)

Synonymes: anticorps Gnb-3, anticorps MGC68913, anticorps MGC130764, anticorps gnb3, anticorps zgc:73058, anticorps zgc:77780, anticorps wu:fk54b04, anticorps gnb3l, anticorps zgc:92641, anticorps G protein subunit beta 3, anticorps guanine nucleotide binding protein (G protein), beta 3, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3b, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3a, anticorps GNB3, anticorps Gnb3, anticorps gnb3.S, anticorps gnb3b, anticorps gnb3a

Sujet: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,GNB3,CSNB1H,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Phospholipase Signaling Pathway,MAPK-JNK Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Blood,Blood Pressure regulation,GNB3

Poids moléculaire: 32 kDa/37 kDa

ID gène: 2784

UniProt: P16520

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction