KAP1 anticorps (AA 576-835)

N° du produit ABIN1683037

Détail du produit anti-KAP1 anticorps

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Épitope: AA 576-835

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: PVLMALAEGP GAEGPRLASP SGSTSSGLEV VAPEGTSAPG GGPGTLDDSA TICRVCQKPG DLVMCNQCEF CFHLDCHLPA LQDVPGEEWS CSLCHVLPDL KEEDGSLSLD GADSTGVVAK LSPANQRKCE RVLLALFCHE PCRPLHQLAT DSTFSLDQPG GTLDLTLIRA RLQEKLSPPY SSPQEFAQDV GRMFKQFNKL TEDKADVQSI IGLQRFFETR MNEAFGDTKF SAVLVEPPPM SLPGAGLSSQ ELSGGPGDGP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 576-835 of human KAP1/KAP1/TRIM28 (NP_005753.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:3000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-KAP1 (ABIN1683037)

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." dans: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Détails sur KAP1

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Autre désignation: TRIM28 (TRIM28 Produits)

Synonymes: anticorps KAP1, anticorps RNF96, anticorps TF1B, anticorps TIF1B, anticorps TRIM28, anticorps kap1, anticorps rnf96, anticorps tf1b, anticorps tif1b, anticorps AA408787, anticorps KAP-1, anticorps KRIP-1, anticorps Tif1b, anticorps Tif1beta, anticorps Kap1, anticorps Krip1, anticorps TIF1BETA, anticorps tripartite motif containing 28, anticorps tripartite motif containing 28 L homeolog, anticorps tripartite motif-containing 28, anticorps TRIM28, anticorps trim28.L, anticorps Trim28

Sujet: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.,KAP1,PPP1R157,RNF96,TF1B,TIF1B,TRIM28,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,TRIM28

Poids moléculaire: 79 kDa/88 kDa

ID gène: 10155

UniProt: Q13263

Pathways: Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus