XRCC1 anticorps (AA 1-320)

N° du produit ABIN1683300

Détail du produit anti-XRCC1 anticorps

Antigène: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Épitope: AA 1-320

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRCC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQLE KEEQIHSVDI GNDGSAFVEV LVGSSAGGAG EQDYEVLLVT SSFMSPSESR SGSNPNRVRM FGPDKLVRAA AEKRWDRVKI VCSQPYSKDS PFGLSFVRFH SPPDKDEAEA PSQKVTVTKL GQFRVKEEDE SANSLRPGAL FFSRINKTSP VTASDPAGPS YAAATLQASS AASSASPVSR AIGSTSKPQE SPKGKRKLDL NQEEKKTPSK PPAQLSPSVP KRPKLPAPTR TPATAPVPAR AQGAVTGKPR GEGTEPRRPR AGPEELGKIL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 (NP_006288.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur XRCC1

Antigène: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Autre désignation: XRCC1 (XRCC1 Produits)

Synonymes: anticorps xrcc1, anticorps MGC80909, anticorps XRCC1, anticorps rcc, anticorps RCC, anticorps Xrcc-1, anticorps X-ray repair complementing defective repair in Chinese hamster cells 1, anticorps X-ray repair cross complementing 1, anticorps xrcc1, anticorps XRCC1, anticorps Xrcc1

Sujet: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.,XRCC1,RCC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,XRCC1

Poids moléculaire: 69 kDa

ID gène: 7515

UniProt: P18887

Pathways: Réparation de l'ADN