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FIP1L1 anticorps (AA 501-594) (Alexa Fluor 350)

FIP1L1 Reactivité: Humain WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN1693391
  • Antigène Voir toutes FIP1L1 Anticorps
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Épitope
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-594
    Reactivité
    • 25
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 2
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FIP1L1 est conjugé à/à la Alexa Fluor 350
    Application
    • 25
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FIP1L1
    Isotype
    IgG
    Top Product
    Discover our top product FIP1L1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Autre désignation
    FIP1L1 (FIP1L1 Produits)
    Synonymes
    anticorps FIP1, anticorps Rhe, anticorps hFip1, anticorps 1300019H17Rik, anticorps Rje, anticorps fip1l1, anticorps wu:fd36f11, anticorps zgc:103421, anticorps factor interacting with PAPOLA and CPSF1, anticorps factor interacting with PAPOLA and CPSF1 S homeolog, anticorps FIP1 like 1 (S. cerevisiae), anticorps FIP1 like 1b (S. cerevisiae), anticorps fip1l1, anticorps FIP1L1, anticorps fip1l1.S, anticorps Fip1l1, anticorps fip1l1b
    Sujet

    Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.

    Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

    ID gène
    81608
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