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PBX3 anticorps (AA 65-130) (Alexa Fluor 350)

PBX3 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN1693450
  • Antigène Voir toutes PBX3 Anticorps
    PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
    Épitope
    • 14
    • 13
    • 9
    • 1
    • 1
    • 1
    AA 65-130
    Reactivité
    • 36
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 34
    • 2
    Lapin
    Clonalité
    • 34
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PBX3 est conjugé à/à la Alexa Fluor 350
    Application
    • 35
    • 20
    • 12
    • 12
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PBX3
    Isotype
    IgG
    Top Product
    Discover our top product PBX3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
    Autre désignation
    PBX3 (PBX3 Produits)
    Synonymes
    anticorps Pbx3b, anticorps pre B cell leukemia homeobox 3, anticorps PBX homeobox 3, anticorps Pbx3, anticorps PBX3
    Sujet

    Synonyms: Homeobox protein PBX3, MGC134053, OTTHUMP00000064213, Pbx 3, Pbx3, PBX3_HUMAN, Pre B cell leukemia homeobox 3, Pre B cell leukemia transcription factor 3, Pre-B-cell leukemia transcription factor 3, RP11 336P12.1.

    Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

    ID gène
    5090
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