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EYA3 anticorps (AA 371-470) (Alexa Fluor 488)

EYA3 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1695802
  • Antigène Voir toutes EYA3 Anticorps
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Épitope
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 371-470
    Reactivité
    • 31
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EYA3 est conjugé à/à la Alexa Fluor 488
    Application
    • 28
    • 12
    • 12
    • 10
    • 7
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EYA3
    Isotype
    IgG
    Top Product
    Discover our top product EYA3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Autre désignation
    EYA3 (EYA3 Produits)
    Synonymes
    anticorps zgc:152966, anticorps si:ch211-195b13.2, anticorps Xeya3, anticorps MGC85199, anticorps EYA3, anticorps AI844637, anticorps EYA transcriptional coactivator and phosphatase 3, anticorps EYA transcriptional coactivator and phosphatase 3 L homeolog, anticorps eya3, anticorps eya3.L, anticorps EYA3, anticorps Eya3
    Sujet

    Synonyms: AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog Drosophila, Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1.

    Background: EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8 % of the human genome.

    ID gène
    2140
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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