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PRICKLE1 anticorps (AA 551-650) (Alexa Fluor 488)

PRICKLE1 Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1695921
  • Antigène Voir toutes PRICKLE1 Anticorps
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    Épitope
    • 14
    • 8
    • 8
    • 2
    AA 551-650
    Reactivité
    • 19
    • 16
    • 3
    Rat
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 32
    • 1
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRICKLE1 est conjugé à/à la Alexa Fluor 488
    Application
    • 18
    • 18
    • 12
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Prickle
    Isotype
    IgG
    Top Product
    Discover our top product PRICKLE1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    Autre désignation
    Prickle (PRICKLE1 Produits)
    Synonymes
    anticorps EPM1B, anticorps RILP, anticorps Rilp, anticorps 1110058P22Rik, anticorps AW215793, anticorps Prickle, anticorps mpk1, anticorps XPk, anticorps pk-B, anticorps prickle, anticorps prickle-B, anticorps Prickle-b, anticorps prickle planar cell polarity protein 1, anticorps prickle planar cell polarity protein 1 L homeolog, anticorps prickle planar cell polarity protein 1 S homeolog, anticorps PRICKLE1, anticorps Prickle1, anticorps prickle1.L, anticorps prickle1.S
    Sujet

    Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.

    Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

    ID gène
    144165
    Pathways
    Signalisation WNT, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
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