APOBEC3B anticorps (Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B) (AA 20-60) (Alexa Fluor 555)

Details for Product anti-APOBEC3B Antibody No. ABIN1696237, Fournisseur: Connectez-vous pour afficher
Antigène
  • APOBEC3H
  • APOBEC3B
  • A3B
  • APOBEC1L
  • ARCD3
  • ARP4
  • DJ742C19.2
  • PHRBNL
  • bK150C2.2
  • APOBEC3F
  • APOBEC3Z2
  • APOBEC3Z3
  • Apobec3
  • Apobec3f
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3
  • apolipoprotein B mRNA editing enzyme catalytic subunit 3B
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
  • APOBEC3Z3
  • APOBEC3B
  • APOBEC3Z2
  • Apobec3b
Épitope
AA 20-60
14
8
8
7
7
3
3
1
1
1
Reactivité
Humain
54
13
5
1
1
1
1
1
1
Hôte
Lapin
51
3
Clonalité
Polyclonal
Conjugué
Cet anticorp APOBEC3B est conjugé à/à la Alexa Fluor 555
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
42
24
12
8
6
4
3
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène KLH conjugated synthetic peptide derived from human APOBEC3B
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others APOBEC3B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Apobec3b (APOBEC3B Antibody Extrait)
Sujet

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.

Subcellular location: Nucleus

Synonyms: A3B, ARP4, ARCD3, PHRBNL, APOBEC1L, bK150C2.2, DJ742C19.2, DNA dC->dU-editing enzyme APOBEC-3B, Phorbolin-1-related protein, Phorbolin-2/3, APOBEC3B

ID gène 9582
UniProt Q9UH17
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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