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DOK7 anticorps (AA 21-120) (Biotin)

DOK7 Reactivité: Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700158
  • Antigène Voir toutes DOK7 Anticorps
    DOK7 (Docking Protein 7 (DOK7))
    Épitope
    • 14
    • 8
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 29
    • 25
    • 15
    Rat
    Hôte
    • 45
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 47
    • 4
    Polyclonal
    Conjugué
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DOK7 est conjugé à/à la Biotin
    Application
    • 40
    • 21
    • 13
    • 13
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DOK7
    Isotype
    IgG
    Top Product
    Discover our top product DOK7 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    DOK7 (Docking Protein 7 (DOK7))
    Autre désignation
    DOK7 (DOK7 Produits)
    Synonymes
    anticorps si:dkey-180b4.3, anticorps si:ch211-164d19.2, anticorps C4orf25, anticorps CMS1B, anticorps A930013K19Rik, anticorps AW049091, anticorps Dok-7, anticorps EF-12, anticorps Oit5, anticorps RGD1566416, anticorps dok-7, anticorps docking protein 7, anticorps DOK7, anticorps dok7, anticorps Dok7
    Sujet

    Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.

    Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.

    Pathways
    Skeletal Muscle Fiber Development
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