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CLEC12A anticorps (AA 61-160) (Biotin)

CLEC12A Reactivité: Humain WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700247
  • Antigène Voir toutes CLEC12A Anticorps
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Épitope
    • 14
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reactivité
    • 44
    • 15
    • 11
    Humain
    Hôte
    • 37
    • 6
    • 3
    • 1
    Lapin
    Clonalité
    • 37
    • 10
    Polyclonal
    Conjugué
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CLEC12A est conjugé à/à la Biotin
    Application
    • 31
    • 15
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CLEC12A
    Isotype
    IgG
    Top Product
    Discover our top product CLEC12A Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Autre désignation
    CLEC12A (CLEC12A Produits)
    Synonymes
    anticorps MGC179455, anticorps CLL-1, anticorps CLL1, anticorps DCAL-2, anticorps MICL, anticorps D230024O04, anticorps KLRL1, anticorps Micl, anticorps C-type lectin domain family 12 member A, anticorps C-type lectin domain family 12, member a, anticorps C-type lectin domain family 12, member A, anticorps CLEC12A, anticorps Clec12a
    Sujet

    Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CL12A_HUMAN, CLEC12A, CLL-1, DCAL-2, Dendritic cell-associated lectin 2, MICL, Myeloid inhibitory C-type lectin-like receptor.

    Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer.

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