GMEB1 anticorps (AA 301-400) (Biotin)

N° du produit ABIN1700878

Détail du produit anti-GMEB1 anticorps (Biotin)

Antigène: GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))

Épitope: AA 301-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GMEB1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GMEB1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GMEB1

Antigène: GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))

Autre désignation: GMEB1 (GMEB1 Produits)

Synonymes: anticorps MGC81052, anticorps GMEB1, anticorps si:ch211-245h7.5, anticorps pif96, anticorps p96pif, anticorps MGC147529, anticorps P96PIF, anticorps PIF96, anticorps 1110050A04Rik, anticorps AI256615, anticorps AI481278, anticorps RGD1563208, anticorps glucocorticoid modulatory element binding protein 1 S homeolog, anticorps glucocorticoid modulatory element binding protein 1, anticorps gmeb1.S, anticorps GMEB1, anticorps gmeb1, anticorps Gmeb1

Sujet:

Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

ID gène: 10691