MS4A2 anticorps (AA 51-150) (Biotin)

N° du produit ABIN1701640

Détail du produit anti-MS4A2 anticorps (Biotin)

Antigène: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Épitope: AA 51-150

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MS4A2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat MS4A2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MS4A2

Antigène: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Autre désignation: MS4A2 (MS4A2 Produits)

Synonymes: anticorps APY, anticorps ATOPY, anticorps FCER1B, anticorps FCERI, anticorps IGEL, anticorps IGER, anticorps IGHER, anticorps MS4A1, anticorps FcRB, anticorps Fce1b, anticorps Fcer1b, anticorps Fcrbeta, anticorps Ms4a1, anticorps fcERI, anticorps FCIGA, anticorps membrane spanning 4-domains A2, anticorps membrane-spanning 4-domains, subfamily A, member 2, anticorps MS4A2, anticorps Ms4a2

Sujet:

Synonyms: FCIGA, Ms4a1, Fcer1b, High affinity immunoglobulin epsilon receptor subunit beta, FcERI, Fc epsilon receptor I beta-chain, IgE Fc receptor subunit beta, Membrane-spanning 4-domains subfamily A member 2, Ms4a2, Fce1b

Background: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

ID gène: 25316

UniProt: P13386

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process