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RUSC1 anticorps (AA 281-380) (Cy5)

RUSC1 Reactivité: Humain, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1704013
  • Antigène Voir toutes RUSC1 Anticorps
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Épitope
    • 14
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 281-380
    Reactivité
    • 27
    • 18
    • 4
    Humain, Souris
    Hôte
    • 25
    • 2
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RUSC1 est conjugé à/à la Cy5
    Application
    • 20
    • 12
    • 12
    • 10
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RUSC1
    Isotype
    IgG
    Top Product
    Discover our top product RUSC1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Autre désignation
    Rusc1 (RUSC1 Produits)
    Synonymes
    anticorps NESCA, anticorps 2210403N08Rik, anticorps AA408288, anticorps RUN and SH3 domain containing 1, anticorps RUSC1, anticorps Rusc1
    Sujet

    Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.

    Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.

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