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POLL anticorps (AA 475-575) (Cy5)

POLL Reactivité: Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1704266
  • Antigène Voir toutes POLL Anticorps
    POLL (Polymerase (DNA Directed), lambda (POLL))
    Épitope
    • 14
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 475-575
    Reactivité
    • 32
    • 22
    • 18
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLL est conjugé à/à la Cy5
    Application
    • 32
    • 15
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
    Isotype
    IgG
    Top Product
    Discover our top product POLL Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    POLL (Polymerase (DNA Directed), lambda (POLL))
    Autre désignation
    DNA Polymerase lambda (POLL Produits)
    Synonymes
    anticorps T10O24.13, anticorps T10O24_13, anticorps zgc:66320, anticorps zgc:77901, anticorps wu:fe49a04, anticorps beta-n, anticorps pol-kappa, anticorps BETAN, anticorps POLKAPPA, anticorps 1110003P06Rik, anticorps AV007317, anticorps DNA polymerase lambda (POLL), anticorps DNA polymerase lambda, anticorps polymerase (DNA directed), lambda, anticorps polymerase (DNA) lambda, anticorps Pol{lambda}, anticorps PTRG_00468, anticorps poll, anticorps POLL, anticorps MCYG_03796, anticorps LOC9325878, anticorps MGYG_02138, anticorps Poll
    Sujet

    Synonyms: BETA N, BETAN, DNA directed DNA polymerase lambda, DNA polymerase beta 2, DNA polymerase beta-2, DNA polymerase kappa, DNA polymerase kappa DNA polymerase beta N, DNA polymerase lambda, DNA polymerase lamda2, DPOLL_HUMAN, EC 2.7.7.7,EC 4.2.99., FLJ46002, OTTHUMP00000020321, OTTHUMP00000020323, OTTHUMP00000059179, Pol beta2, POL KAPPA, Pol Lambda, POLKAPPA, POLL, Polymerase DNA directed lambda.

    Background: DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.

    ID gène
    27343
    Pathways
    Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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