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KIT anticorps (pTyr568, pTyr570) (Cy5)

KIT Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1704371
  • Antigène Voir toutes KIT Anticorps
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Épitope
    • 55
    • 55
    • 35
    • 28
    • 23
    • 23
    • 22
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 13
    • 12
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    pTyr568, pTyr570
    Reactivité
    • 674
    • 241
    • 66
    • 29
    • 28
    • 28
    • 17
    • 13
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 601
    • 107
    • 48
    • 2
    • 1
    Lapin
    Clonalité
    • 593
    • 166
    • 1
    Polyclonal
    Conjugué
    • 231
    • 81
    • 78
    • 77
    • 62
    • 60
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KIT est conjugé à/à la Cy5
    Application
    • 431
    • 394
    • 298
    • 147
    • 91
    • 91
    • 68
    • 50
    • 46
    • 46
    • 34
    • 25
    • 10
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570
    Isotype
    IgG
    Top Product
    Discover our top product KIT Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Autre désignation
    c-Kit + (KIT Produits)
    Synonymes
    anticorps C-Kit, anticorps CD117, anticorps PBT, anticorps SCFR, anticorps Bs, anticorps Fdc, anticorps Gsfsco1, anticorps Gsfsco5, anticorps Gsfsow3, anticorps SCO1, anticorps SCO5, anticorps SOW3, anticorps Ssm, anticorps Tr-kit, anticorps W, anticorps c-KIT, anticorps c-kit, anticorps MGF, anticorps KIT, anticorps C-KIT, anticorps kit, anticorps receptor, anticorps sparse, anticorps Xkl-1, anticorps kit-a, anticorps kit-b, anticorps kl1-A, anticorps krk1, anticorps pbt, anticorps scfr, anticorps KIT proto-oncogene receptor tyrosine kinase, anticorps v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a, anticorps KIT proto-oncogene receptor tyrosine kinase S homeolog, anticorps KIT, anticorps Kit, anticorps kita, anticorps kit, anticorps kit.S
    Sujet

    Synonyms: c-Kit phospho Y568 + Y570, p-c-Kit phospho Y568 + Y570, C Kit, c-Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, p145 c-kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, soluble KIT variant 1, Stem cell factor receptor, tyrosine protein kinase Kit, Tyrosine-protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.

    Background: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

    ID gène
    3815
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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