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PIK3 gamma (pSer1101) anticorps (Cy5) Primary Antibody

Reactivité: Humain, Souris, Rat IF (p) Hôte: Lapin Polyclonal
N° du produit ABIN1704380
$453.20
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 14 à 21 jours ouvrables
  • Antigène
    Épitope
    pSer1101
    Reactivité
    Humain, Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Conjugué
    Cy5
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human PIK3 gamma around the phosphorylation site of Ser1101
    Isotype
    IgG
  • Antigène
    Sujet

    This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

    Subcellular location: Secreted

    Synonyms: PK3CG_HUMAN, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma, PtdIns-3-kinase subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, PtdIns-3-kinase subunit p110-gamma, p110gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, Serine/threonine protein kinase PIK3CG, 1 phosphatidylinositol 3 kinase, p120-PI3K, p120 PI3K, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, p110 gamma, Phosphatidylinositol 3 kinase catalytic 110 kD gamma,

    ID gène
    5294
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 4°C
    Date de péremption
    12 months
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