ABCB7 anticorps (AA 201-300) (Cy5)

N° du produit ABIN1704708

Détail du produit anti-ABCB7 anticorps (Cy5)

Antigène: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB7 est conjugé à/à la Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ABCB7

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ABCB7

Antigène: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Autre désignation: ABCB7 (ABCB7 Produits)

Synonymes: anticorps CG7955, anticorps Dmel\\CG7955, anticorps dABCB7, anticorps GB11034, anticorps ABCB7, anticorps fc20c02, anticorps wu:fc20c02, anticorps ABC7, anticorps ASAT, anticorps Atm1p, anticorps EST140535, anticorps AA517758, anticorps AU019072, anticorps Abc7, anticorps ATP binding cassette subfamily B member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial-like, anticorps ABCB7, anticorps LOC412749, anticorps abcb7, anticorps LOC100367778, anticorps LOC100467128, anticorps Abcb7

Sujet:

Synonyms: ABC transporter 7 protein, ABC7, Abcb7, ABCB7_HUMAN, ASAT, Atm1p, ATP binding cassette 7, ATP binding cassette sub family B MDR/TAP member 7, ATP binding cassette sub family B member 7, ATP binding cassette sub family B member 7 mitochondrial, ATP binding cassette transporter 7, ATP-binding cassette sub-family B member 7, ATP-binding cassette transporter 7, EST140535, MDR7, mitochondrial, Multidrug resistance protein 7, P-glycoprotein 7, PGP7.

Background: The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD14 that are known to be present in the human peroxisome membrane (1). All four proteins are ABC half-transporters, which dimerize to form an active transporter (1). A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage (2,3). ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD (4). The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3 (5). ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors (5). ABCD4 localizes to peroxisomes (1). The genes which encode ABCD14 map to human chromosome Xq28, 12q11-q12, 1p22-p21 and 14q24.3, respectively (3,68). ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13.1-q13.3 (9).

ID gène: 22

Pathways: Transition Metal Ion Homeostasis