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Complement Component C9b (C9b) (AA 251-350) anticorps (Cy5)

C9b Reactivité: Humain, Souris WB, FACS Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1704835
  • Antigène Voir toutes Complement Component C9b (C9b) Anticorps
    Complement Component C9b (C9b)
    Épitope
    • 15
    • 15
    AA 251-350
    Reactivité
    Humain, Souris
    Hôte
    • 30
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cy5
    Application
    • 30
    • 13
    • 13
    • 13
    • 6
    • 6
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Complement component C9b
    Isotype
    IgG
    Top Product
    Discover our top product C9b Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Complement Component C9b (C9b)
    Autre désignation
    Complement component C9b (C9b Produits)
    Synonymes
    anticorps C9, anticorps complement C9, anticorps proteasome (prosome, macropain) subunit, alpha type 4, anticorps C9, anticorps Psma4
    Sujet

    Synonyms: CO9_HUMAN, Complement component C9, Complementcomponent C9b.

    Background: C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 Molecules. These polymerized C9 Molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.

    ID gène
    735
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