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WDFY1 anticorps (AA 21-120) (Cy5.5)

WDFY1 Reactivité: Rat FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1706835
  • Antigène Voir toutes WDFY1 Anticorps
    WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))
    Épitope
    • 15
    • 6
    • 3
    • 1
    • 1
    AA 21-120
    Reactivité
    • 19
    • 17
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 31
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WDFY1 est conjugé à/à la Cy5.5
    Application
    • 13
    • 12
    • 12
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human WDFY1
    Isotype
    IgG
    Top Product
    Discover our top product WDFY1 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))
    Autre désignation
    WDFY1 + WDFY2 (WDFY1 Produits)
    Synonymes
    anticorps FENS-1, anticorps WDF1, anticorps ZFYVE17, anticorps 1700013B03Rik, anticorps 1700120F24Rik, anticorps Jr1, anticorps mKIAA1435, anticorps MGC93914, anticorps zgc:101764, anticorps zgc:109909, anticorps WD repeat and FYVE domain containing 1, anticorps WDFY1, anticorps Wdfy1, anticorps wdfy1
    Sujet

    Synonyms: FENS 1, FENS-1, FENS1, KIAA1435, Phosphoinositide binding protein 1, Phosphoinositide binding protein SR1, Phosphoinositide-binding protein 1, WD repeat and FYVE domain containing 1, WD repeat and FYVE domain-containing protein 1, WD40 and FYVE domain containing protein 1, WD40- and FYVE domain-containing protein 1, WDF1, WDFY1, WDFY1_HUMAN, ZFYVE17, Zinc finger FYVE domain containing protein 17, Zinc finger FYVE domain-containing protein 17, WDFY2, WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein, WD40- and FYVE domain-containing protein 2, Zinc finger FYVE domain-containing protein 22, WDF2, ZFYVE22

    Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDFY1 positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. WDFY1 Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. WDFY2 acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2. WDFY2 positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1

    ID gène
    57590, 115825
    UniProt
    Q8IWB7, Q96P53
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