CYP2A6 anticorps (AA 388-494) (HRP)

N° du produit ABIN1712030

Détail du produit anti-CYP2A6 anticorps (HRP)

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Épitope: AA 388-494

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2A6 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CYP2A/Cytochrome P450 2A6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CYP2A6

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Autre désignation: CYP2A/Cytochrome P450 2A6 (CYP2A6 Produits)

Synonymes: anticorps CPA6, anticorps CYP2A, anticorps CYP2A3, anticorps CYPIIA6, anticorps P450C2A, anticorps P450PB, anticorps cyp2a6, anticorps cytochrome P450 family 2 subfamily A member 6, anticorps cytochrome P450 2A6, anticorps cytochrome P450 family 2 subfamily A member 6 L homeolog, anticorps CYP2A6, anticorps cyp2a6.L

Sujet:

Synonyms: Coumarin 7 hydroxylase, Coumarin 7-hydroxylase, CP2A6_HUMAN, CPA6, CYP2A, CYP2A3, CYP2A6, CYPIIA6, Cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450 subfamily IIA phenobarbital inducible polypeptide 6, Cytochrome P450I, Cytochrome P450, family 2 subfamily A polypeptide 6, Flavoprotein linked monooxygenase, P450C2A, P450PB, Xenobiotic monooxygenase.

Background: P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds (1). Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies (2). NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle (3,4). NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5 (5,6). NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin (7). Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively (8).

ID gène: 1548