FDPS anticorps (AA 201-300) (HRP)

N° du produit ABIN1712050

Détail du produit anti-FDPS anticorps (HRP)

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Épitope: AA 201-300

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDPS est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FDPS

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FDPS

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Autre désignation: FDPS (FDPS Produits)

Synonymes: anticorps CG12389, anticorps DmFPPS, anticorps DmFPPSase, anticorps DmFPS, anticorps Dmel\\CG12389, anticorps FPS, anticorps fpps, anticorps fps, anticorps l(2)k06103, anticorps v(2)k03514, anticorps NCU01175.1, anticorps 16.m00760, anticorps DDBDRAFT_0206220, anticorps DDBDRAFT_0215017, anticorps DDB_0206220, anticorps DDB_0215017, anticorps FPPS, anticorps Ac2-125, anticorps (2E, anticorps 6030492I17Rik, anticorps AI256750, anticorps Fdpsl1, anticorps mKIAA1293, anticorps Farnesyl pyrophosphate synthase, anticorps farnesyl diphosphate synthase, anticorps farnesyl diphosphate synthase L homeolog, anticorps farnesyl pyrophosphate synthase, anticorps farnesyl pyrophosphate synthetase, anticorps farnesyl-pyrophosphate synthetase, anticorps FDP synthase, anticorps Farnesyl pyrophosphate synthetase, anticorps farnesyl diphosphate synthetase, anticorps farnesyl pyrophosphate synthase 1, anticorps Fpps, anticorps fdps, anticorps fdps.L, anticorps MGG_08649, anticorps TP03_0857, anticorps Tb09.160.4300, anticorps fpp, anticorps BBOV_I000120, anticorps fps, anticorps fpps, anticorps FDPS, anticorps Fdps, anticorps fps1

Sujet:

Synonyms: 2E,6E farnesyl diphosphate synthase, 6E-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyl diphosphate synthetase, Farnesyl pyrophosphate synthase, Farnesyl pyrophosphate synthetase, Fdps, FPP synthase, FPP synthetase, FPPS, FPPS_HUMAN, FPS, Geranyltranstransferase.

Background: FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.

ID gène: 2224

Pathways: Regulation of Muscle Cell Differentiation