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SIX2 anticorps (AA 101-200) (HRP)

SIX2 Reactivité: Humain WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712087
  • Antigène Voir toutes SIX2 Anticorps
    SIX2 (SIX Homeobox 2 (SIX2))
    Épitope
    • 14
    • 9
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 45
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 3
    Lapin
    Clonalité
    • 43
    • 3
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIX2 est conjugé à/à la HRP
    Application
    • 39
    • 22
    • 13
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SIX2
    Isotype
    IgG
    Top Product
    Discover our top product SIX2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SIX2 (SIX Homeobox 2 (SIX2))
    Autre désignation
    SIX2 (SIX2 Produits)
    Synonymes
    anticorps six2-A, anticorps zgc:195089, anticorps zgc:195096, anticorps six2.1, anticorps wu:fj04e08, anticorps zgc:91945, anticorps SIX homeobox 2, anticorps sine oculis-related homeobox 2, anticorps SIX homeobox 2 S homeolog, anticorps SIX homeobox 2b, anticorps SIX homeobox 2a, anticorps SIX2, anticorps Six2, anticorps six2.S, anticorps six2b, anticorps six2a
    Sujet

    Synonyms: Homeobox protein SIX2, OTTHUMP00000201649, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, SIX homeobox 2, Six2, SIX2_HUMAN.

    Background: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.

    ID gène
    10736
    Pathways
    Protein targeting to Nucleus
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