AMHR2 anticorps (AA 21-120) (HRP)

N° du produit ABIN1712149

Détail du produit anti-AMHR2 anticorps (HRP)

Antigène: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMHR2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MISRII/AMHR2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AMHR2

Antigène: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Autre désignation: AMHR2 (AMHR2 Produits)

Synonymes: anticorps AMHR, anticorps MISR2, anticorps MISRII, anticorps MRII, anticorps Misiir, anticorps Misrii, anticorps Mrii, anticorps anti-Mullerian hormone receptor type 2, anticorps anti-Mullerian hormone type 2 receptor, anticorps AMHR2, anticorps Amhr2

Sujet:

Synonyms: AMH type II receptor, AMHR2, AMHR2_HUMAN, Anti-Muellerian hormone type II receptor, Anti-Muellerian hormone type-2 receptor, MGC141312, MIS type II receptor, MISRII, MRII, Muellerian hormone type 2 receptor, Muellerian hormone type II receptor, Mullerian hormone receptor type II.

Background: MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

ID gène: 269