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Representing about 2 % of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf79 gene product has been provisionally designated C20orf79 pending further characterization.
Synonyms: Chromosome 20 open reading frame 79, dJ1068E13.2, HSD22, Hypothetical protein LOC140856, MGC138229, OTTHUMP00000030367, Sterol carrier protein 2 like protein, Uncharacterized protein C20orf79.