This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
Subcellular location: Extracellular
Synonyms: Gamma-glutamyltransferase 7 heavy chain, D20S101, dJ18C9.2, Gamma glutamyltransferase 4, Gamma glutamyltransferase 7, Gamma glutamyltransferase like 3, Gamma glutamyltransferase like 5, Gamma glutamyltranspeptidase 7, Gamma glutamyltranspeptidase like 3, GGT 7, GGT4, GGTL3, GGTL5, GGT7_HUMAN.