The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].
Synonyms: histidine triad nucleotide binding protein 1, Adenosine 5' monophosphoramidase, Adenosine 5'-monophosphoramidase, HINT 1, HINT-1, histidine triad nucleotide binding protein 1, histidine triad nucleotide binding protein, histidine triad nucleotide-binding protein, Histidine triad nucleotide-binding protein 1, PKCI 1, PKCI-1, PKCI1, PRKCNH1, Protein kinase C inhibitor 1, Protein kinase C interacting protein 1, Protein kinase C-interacting protein 1, HINT1_HUMAN.