NAC1 anticorps (AA 311-400) (HRP)

N° du produit ABIN1712365

Détail du produit anti-NAC1 anticorps (HRP)

Antigène: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Épitope: AA 311-400

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAC1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NAC1/BTBD14B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NAC1

Antigène: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Autre désignation: NAC1/BTBD14B (NACC1 Produits)

Synonymes: anticorps BEND8, anticorps BTBD14B, anticorps BTBD30, anticorps NAC-1, anticorps NAC1, anticorps NACC1, anticorps 2010001H03Rik, anticorps 4930511N13Rik, anticorps Btbd14b, anticorps Nac1, anticorps Nac-1, anticorps nucleus accumbens associated 1, anticorps nucleus accumbens associated 1, BEN and BTB (POZ) domain containing, anticorps NACC1, anticorps Nacc1

Sujet:

Synonyms: BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, btbd14b, FLJ37383, NAC-1, NAC1, Nacc1, NACC1_HUMAN, Nucleus accumbens-associated protein 1.

Background: NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.

ID gène: 112939