ABL1 anticorps (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase) (pThr754) (HRP)

Details for Product anti-ABL1 Antibody No. ABIN1712438, Fournisseur: Connectez-vous pour afficher
Antigène
  • ABL
  • JTK7
  • bcr/abl
  • c-ABL
  • p150
  • v-abl
  • AI325092
  • Abl
  • E430008G22Rik
  • c-Abl
  • ABL proto-oncogene 1, non-receptor tyrosine kinase
  • c-abl oncogene 1, non-receptor tyrosine kinase
  • Tyrosine-protein kinase abl-1
  • ABL1
  • Abl1
  • abl-1
  • abl1
Épitope
pThr754, pThr735
56
47
43
33
31
28
25
16
16
16
16
15
15
15
15
15
15
15
15
15
13
12
11
9
7
7
5
5
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
601
388
309
10
7
1
1
1
1
Hôte
Lapin
603
21
Clonalité
Polyclonal
Conjugué
Cet anticorp ABL1 est conjugé à/à la HRP
31
31
28
16
16
16
15
15
15
15
15
15
15
15
15
15
15
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
355
195
195
165
113
64
44
21
16
11
6
2
2
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Thr754
Isotype IgG
Purification Purified by Protein A.
Autre désignation C-Abl (ABL1 Antibody Extrait)
Sujet

The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9,22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.

Synonyms: c-AblThr754/Thr735, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, ABL, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, p150, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, v abl Abelson murine leukemia viral oncogene homolog 1, v abl, ABL1_HUMAN.

ID gène 25
Pathways Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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