ARHGEF11 anticorps (AA 451-550) (HRP)

N° du produit ABIN1712470

Détail du produit anti-ARHGEF11 anticorps (HRP)

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Épitope: AA 451-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF11 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ARHGEF11

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Autre désignation: PDZ RHOGEF/GTRAP48 (ARHGEF11 Produits)

Synonymes: anticorps ARHGEF11, anticorps GTRAP48, anticorps PDZ-RHOGEF, anticorps B930073M02, anticorps E130307F09, anticorps PDZ-RhoGEF, anticorps Prg, anticorps RhoGEF, anticorps mKIAA0380, anticorps Gtrap48, anticorps Rho guanine nucleotide exchange factor (GEF) 11, anticorps Rho guanine nucleotide exchange factor 11, anticorps rho guanine nucleotide exchange factor 11, anticorps arhgef11, anticorps ARHGEF11, anticorps Arhgef11, anticorps LOC511220

Sujet:

Synonyms: PDZ-RhoGEF, ARHGB_HUMAN, ARHGEF 11, ARHGEF11, DKFZp667F1223, Glutamate transporter EAAT4 associated protein 48, GTRAP 48, GTRAP48, PDZ RhoGEF, Rho guanine exchange factor GEF 11, Rho guanine nucleotide exchange factor GEF 11, Rho guanine nucleotide exchange factor 11, RhoA specic guanine nucleotide exchange factor, RhoGEF glutamate transport modulator.

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling