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SKAP1 anticorps (AA 101-200) (HRP)

SKAP1 Reactivité: Rat ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712604
  • Antigène Voir toutes SKAP1 Anticorps
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    Épitope
    • 14
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 35
    • 21
    • 6
    • 3
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 46
    • 4
    • 1
    Lapin
    Clonalité
    • 47
    • 4
    Polyclonal
    Conjugué
    • 21
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SKAP1 est conjugé à/à la HRP
    Application
    • 32
    • 28
    • 13
    • 13
    • 9
    • 7
    • 4
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SKAP55
    Isotype
    IgG
    Top Product
    Discover our top product SKAP1 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    Autre désignation
    SKAP55 (SKAP1 Produits)
    Synonymes
    anticorps 1700091G21Rik, anticorps Scap1, anticorps Skap-55, anticorps SCAP1, anticorps SKAP55, anticorps Skap55, anticorps src family associated phosphoprotein 1, anticorps src kinase associated phosphoprotein 1, anticorps Skap1, anticorps SKAP1
    Sujet

    Synonyms: pp55, SCAP 1, SCAP1, SKAP 1, SKAP 55, SKAP-55, Skap1, SKAP1_HUMAN, SKAP55 adaptor protein, SRC family associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase associated phosphoprotein 1, SRC kinase associated phosphoprotein 55 kD, Src kinase associated phosphoprotein of 55 kDa, Src kinase-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa.

    Background: Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines. SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.

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