GABPA anticorps (AA 51-150)

N° du produit ABIN1714176

Détail du produit anti-GABPA anticorps

Antigène: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Épitope: AA 51-150

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABPA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GABPA/NRF2A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GABPA (ABIN1714176)

Chang, Wu, Xu, Liao, Wu, Cheng: "Scopoletin Protects against Methylglyoxal-Induced Hyperglycemia and Insulin Resistance Mediated by Suppression of Advanced Glycation Endproducts (AGEs) Generation and Anti-Glycation." dans: Molecules (Basel, Switzerland), Vol. 20, Issue 2, pp. 2786-801, (2015) (PubMed).

Détails sur GABPA

Antigène: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Autre désignation: GABPA/NRF2A (GABPA Produits)

Synonymes: anticorps gabpa-A, anticorps XrpFI, anticorps X-alpha1, anticorps GABPA, anticorps nft2, anticorps nrf2, anticorps nrf2a, anticorps e4tf1a, anticorps e4tf1-60, anticorps Nrf-2alpha, anticorps Nrf2a, anticorps E4TF1-60, anticorps E4TF1A, anticorps NFT2, anticorps NRF2, anticorps NRF2A, anticorps RCH04A07, anticorps GABPalpha, anticorps e4tf, anticorps wu:fc12d11, anticorps GA binding protein transcription factor alpha subunit S homeolog, anticorps GA binding protein transcription factor alpha subunit, anticorps GA binding protein transcription factor, alpha subunit, anticorps GA binding protein transcription factor alpha subunit L homeolog, anticorps GA repeat binding protein, alpha, anticorps gabpa.S, anticorps GABPA, anticorps gabpa, anticorps Gabpa, anticorps gabpa.L

Sujet:

Synonyms: E4TF 1A, E4TF1 60, E4TF1A, GA binding protein alpha chain, GA binding protein transcription factor alpha subunit 60 kDa, GA binding protein transcription factor alpha subunit, GA-binding protein alpha chain, GABP A, GABP alpha subunit, GABP alpha subunit, GABP subunit alpha, Gabpa, GABPA_HUMAN, Human nuclear respiratory factor 2 subunit alpha, NFT 2, NFT2, NRF 2, NRF 2A, NRF2, NRF2A, Nuclear respiratory factor 2 alpha subunit, Nuclear respiratory factor 2 subunit alpha, Nuclear respiratory factor 2 subunit alpha, RCH04A07, Transcription factor E4TF1 60, Transcription factor E4TF1 60, Transcription factor E4TF1-60.

Background: The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.

ID gène: 2551

Pathways: Myometrial Relaxation and Contraction