GANC anticorps (AA 31-130)

N° du produit ABIN1714452

Détail du produit anti-GANC anticorps

Antigène: GANC (Glucosidase, Alpha, Neutral C (GANC))

Épitope: AA 31-130

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GANC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GANC (ABIN1714452)

Wang, Liu, Wang, Yang, Li, Ding, Sun, Bai, Li: "Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 2305683, (2018) (PubMed).

Détails sur GANC

Antigène: GANC (Glucosidase, Alpha, Neutral C (GANC))

Autre désignation: GANC/Neutral alphaglucosidase C (GANC Produits)

Synonymes: anticorps 5830445O15Rik, anticorps 9330160A12, anticorps mFLJ00088, anticorps glucosidase alpha, neutral C, anticorps calpain-3, anticorps glucosidase, alpha; neutral C, anticorps GANC, anticorps LOC453361, anticorps ganc, anticorps Ganc

Sujet:

Synonyms: Ganc, GANC_HUMAN, Glucosidase alpha neutral C, MGC138256, Neutral alpha glucosidase C, Neutral alpha-glucosidase C, Neutral alphaglucosidase C.

Background: A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, neutral C) is a 914 amino acid protein with -glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked -D-glucose residues and releases -D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

ID gène: 2595